Round of 32 draw
FC Porto (POR, holders) v Manchester City FC (ENG)
AFC Ajax (NED) v Manchester United FC (ENG)
FC Lokomotiv Moskva (RUS) v Athletic Club (ESP)
FC Salzburg (AUT) v FC Metalist Kharkiv (UKR)
Stoke City FC (ENG) v Valencia CF (ESP)
FC Rubin Kazan (RUS) v Olympiacos FC (GRE)
AZ Alkmaar (NED) v RSC Anderlecht (BEL)
S.S. Lazio (ITA) v Club Atlético de Madrid (ESP)
FC Steaua Bucureşti (ROU) v FC Twente (NED)
FC Viktoria Plzeň (CZE) v FC Schalke 04 (GER)
Wisła Kraków (POL) v R. Standard de Liège (BEL)
SC Braga (POR) v Beşiktaş JK (TUR)
Udinese Calcio (ITA) v PAOK FC (GRE)
Trabzonspor AŞ (TUR) v PSV Eindhoven (NED)
Hannover 96 (GER) v Club Brugge KV (BEL)
Legia Warszawa (POR) v Sporting Clube de Portugal (POR)

Round of 16 draw
Salzburg/Metalist v Rubin/Olympiacos
Legia/Sporting v Porto/Manchester City
Steaua/Twente v Plzeň/Schalke
Wisła/Standard v Hannover/Brugge
Stoke/Valencia v Trabzonspor/PSV
Alkmaar/Anderlecht v Udinese/PAOK
Lazio/Atlético v Braga/Beşiktaş
Porto/Manchester United v Lokomotiv/Athletic

13.00CET, 16 December, Nyon
The draw for the round of 32 played on 16 and 23 February includes the top two teams from each of the 12 groups along with the eight sides transferring from the UEFA Champions League after finishing third in their pools.

The UEFA Europa League group winners are all seeded, along with the four UEFA Champions League qualifiers with the best record in their section. The other four sides transferring from the elite competition and the UEFA Europa League group runners-up are in the unseeded pot and are drawn first, meaning they are drawn to play the first-leg matches at home. They cannot be paired with either the winners from their section or clubs from the same association.

Seeded
PAOK FC, R. Standard de Liège, PSV Eindhoven, Sporting Clube de Portugal, Beşiktaş JK, Athletic Club, FC Metalist Kharkiv, Club Brugge KV, Club Atlético de Madrid, FC Schalke 04, FC Twente, RSC Anderlecht, Manchester City FC*, Manchester United FC*, Valencia CF*, Olympiacos CF*

Unseeded
FC Rubin Kazan, Hannover 96, Legia Warszawa, S.S. Lazio, Stoke City FC, FC Salzburg, AZ Alkmaar, SC Braga, Udinese Calcio, FC Steaua Bucureşti, Wisła Kraków, FC Lokomotiv Moskva, Trabzonspor AŞ*, AFC Ajax*, FC Porto*, FC Viktoria Plzeň*

*Transferred from the UEFA Champions League

The draw for the round of 16 on 8 and 15 March follows and there are no seeded teams. The 16 balls containing slips of paper for 'Winners of match 1' to 'Winners of match 16' are placed in one bowl and shuffled. The first team drawn are to play their first match at home against the second team drawn and the same procedure is then repeated for the other matches. There are no restrictions on the round of 16 draw.